MLHC is an annual research meeting that exists to bring together two usually insular disciplines: computer scientists with artificial intelligence, machine learning, and big data expertise, and clinicians/medical researchers. MLHC supports the advancement of data analytics, knowledge discovery, and meaningful use of complex medical data by fostering collaborations and the exchange of ideas between members of these often completely separated communities. To pursue this goal, the event includes invited talks, poster presentations, panels, and ample time for thoughtful discussion and robust debate.